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  3. KOdiA-PC

氧化的低密度脂蛋白 (oxLDL) 颗粒包含具有细胞毒性和促动脉粥样硬化的低分子量物质。许多这些物质最近从 oxLDL 中分离和纯化,并被鉴定为磷脂酰胆碱种类,其在 sn-2 位置含有片段化的氧化短链脂肪酸残余物。 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl) 磷脂酰胆碱或 KOdiA-PC 是 oxLDL 种类中最有效的 CD36 配体之一。 KOdiA-PC 以仅 2 至 3 个 KOdiA-PC 分子/LDL 颗粒的频率赋予 CD36 清道夫受体与 LDL 的结合亲和力,并且可能是 oxLDL 更重要的结构决定因素之一。

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KOdiA-PC Chemical Structure

KOdiA-PC Chemical Structure

CAS No. : 439904-33-3

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规格 价格 是否有货 数量
500μg (7.53 mM * 100 μL in Ethanol) ¥2000
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1mg (7.53 mM * 200 μL in Ethanol) ¥3200
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  • 生物活性

  • 纯度 & 产品资料

生物活性

Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species that are cytotoxic and proatherogenic. Many of these species were recently isolated and purified from oxLDL and identified as phosphatidylcholine species containing fragmented oxidized short-chain fatty acid residues at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine or KOdiA-PC is one of the most potent CD36 ligands of the oxLDL species. KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle and may be one of the more important structural determinants of oxLDL.

分子量

663.78

Formula

C32H58NO11P

CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Solution, -20°C, 2 years

纯度 & 产品资料

纯度: ≥99.0%

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产品名称:
KOdiA-PC
目录号:
HY-126726
需求量: